Abstract
Objective: This study aims to determine the frequency of incidental lung cancers detected during chest computed tomography
(CT) scans performed for guiding the diagnosis or treatment of coronavirus disease-2019 (COVID-19). Material and Methods: In this single-
center retrospective study, the chest CT scans taken during the beginning of COVID-19 pneumonia (mostly pre-vaccination era) between
April 2020 and December 2020 were examined. Patients who were younger than 18 years and those with a prior history of cancer were excluded.
Moreover, the clinicopathological factors and radiologic findings of those patients with pulmonary nodule size on CT ≥3 mm or
masses were recorded. Results: We assessed the CT scans of 2994 patients. A pulmonary nodule ≥3 mm or a mass was detected in 473 patients,
while nine of them were diagnosed with lung cancer. The median age of lung cancer patients was 65 years (48-71 years). The most common
subtype of lung cancer was adenocarcinoma (44.4%), followed by squamous cell carcinoma (33.3%) and small cell lung cancer (22.2%).
Furthermore, all patients were diagnosed at the non-metastatic stage. Conclusion: Our study showed that early-stage lung cancers were detected
incidentally on CT scans in suspected COVID-19 pneumonia patients. While the COVID-19 pandemic resulted in significant mortality
worldwide, early diagnosis and treatment of these cases can save several lives.
Keywords:
Cancer screening, COVID-19, incidence, incidental finding, lung cancer
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